Technology is changing the way we live and work faster than ever before. Over the last decade, the world witnessed disruption in most major industries, and almost 90% of American adults will have a smartphone by 2020. While many of these changes improved human productivity and welfare, others increased inequality, corruption, and even violence. Some innovations brought both. Tech Conference 25 is therefore focused on a discussion of two key questions: What changes does the next decade hold? How can we apply the lessons we learned from the past decade—technical, organizational, and social—to avoid making the same mistakes again?